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Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity

BACKGROUND: Autosomal recessive juvenile parkinsonism (AR-JP) is caused by mutations in the parkin gene which encodes an E3 ubiquitin-protein ligase. Parkin is thought to be critical for protecting dopaminergic neurons from toxic insults by targeting misfolded or oxidatively damaged proteins for pro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Perez, Francisco A, Curtis, Wendy R, Palmiter, Richard D
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351194/
https://ncbi.nlm.nih.gov/pubmed/16375772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-6-71
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