Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen

Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we analyzed the genome sequences of eight GBS isolates and cloned and tested 312 surface proteins as vaccines. Four protei...

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Main Authors: Maione, Domenico, Margarit, Immaculada, Rinaudo, Cira D., Masignani, Vega, Mora, Marirosa, Scarselli, Maria, Tettelin, Hervé, Brettoni, Cecilia, Iacobini, Emilia T., Rosini, Roberto, D’Agostino, Nunzio, Miorin, Lisa, Buccato, Scilla, Mariani, Massimo, Galli, Giuliano, Nogarotto, Renzo, Dei, Vincenzo Nardi, Vegni, Filipo, Fraser, Claire, Mancuso, Giuseppe, Teti, Giuseppe, Madoff, Lawrence C., Paoletti, Lawrence C., Rappuoli, Rino, Kasper, Dennis L., Telford, John L., Grandi, Guido
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351092/
https://ncbi.nlm.nih.gov/pubmed/15994562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1109869
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