The Group B Streptococcus–Secreted Protein CIP Interacts with C4, Preventing C3b Deposition via the Lectin and Classical Complement Pathways

The group B Streptococcus (GBS) is a leading cause of neonatal invasive disease. GBS bacteria are surrounded by a thick capsular polysaccharide that is a potent inhibitor of complement deposition via the alternative pathway. Several of its surface molecules can however activate the classical and lec...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Pietrocola, Giampiero, Rindi, Simonetta, Rosini, Roberto, Buccato, Scilla, Speziale, Pietro, Margarit, Immaculada
Format: Artigo
Language:Inglês
Published: AAI 2016
Subjects:
Infectious Disease and Host Response
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683360/
https://ncbi.nlm.nih.gov/pubmed/26608922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501954
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items