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PDX-1 LINKS HISTONE H3-LYS4 METHYLATION TO RNA POLYMERASE II ELONGATION DURING ACTIVATION OF INSULIN TRANSCRIPTION

Expression of the insulin gene is nearly exclusive to the β cells of the pancreatic islets. Whereas the sequence-specific transcription factors that regulate insulin expression have been well studied, the interrelationship between these factors, chromatin structure, and transcriptional elongation by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Francis, Joshua, Chakrabarti, Swarup K., Garmey, James C., Mirmira, Raghavendra G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351077/
https://ncbi.nlm.nih.gov/pubmed/16141209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M505741200
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