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Induction of Higher Avidity Human CTL by Vector-Mediated Enhanced Costimulation of Antigen-Presenting Cells

It is believed that the efficacy of antigen-specific CD8(+) cytotoxic T lymphocytes (CTLs) depends not only on the quantity of CTL generated, but perhaps, more importantly, on the avidity of the CTL. To date, however, no strategy has been demonstrated to preferentially induce higher avidity human CT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Sixun, Tsang, Kwong-Yok, Schlom, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351007/
https://ncbi.nlm.nih.gov/pubmed/16061879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-0670
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