Connexin43-dependent mechanism modulates renin secretion and hypertension

To investigate the function of Cx43 during hypertension, we studied the mouse line Cx43KI32 (KI32), in which the coding region of Cx32 replaces that of Cx43. Within the kidneys of homozygous KI32 mice, Cx32 was expressed in cortical and medullary tubules, as well as in some extra- and intraglomerula...

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Autors principals: Haefliger, Jacques-Antoine, Krattinger, Nathalie, Martin, David, Pedrazzini, Thierry, Capponi, Alessandro, Döring, Britta, Plum, Achim, Charollais, Anne, Willecke, Klaus, Meda, Paolo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350996/
https://ncbi.nlm.nih.gov/pubmed/16440062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23327
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