Connexins protect mouse pancreatic β cells against apoptosis

Type 1 diabetes develops when most insulin-producing β cells of the pancreas are killed by an autoimmune attack. The in vivo conditions modulating the sensitivity and resistance of β cells to this attack remain largely obscure. Here, we show that connexin 36 (Cx36), a trans-membrane protein that for...

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Hlavní autoři: Klee, Philippe, Allagnat, Florent, Pontes, Helena, Cederroth, Manon, Charollais, Anne, Caille, Dorothée, Britan, Aurore, Haefliger, Jacques-Antoine, Meda, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225984/
https://ncbi.nlm.nih.gov/pubmed/22056383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40509
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