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CcaR Is an Autoregulatory Protein That Binds to the ccaR and cefD-cmcI Promoters of the Cephamycin C-Clavulanic Acid Cluster in Streptomyces clavuligerus

The putative regulatory CcaR protein, which is encoded in the β-lactam supercluster of Streptomyces clavuligerus, has been partially purified by ammonium sulfate precipitation and heparin affinity chromatography. In addition, it was expressed in Escherichia coli, purified as a His-tagged recombinant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Santamarta, Irene, Rodríguez-García, Antonio, Pérez-Redondo, Rosario, Martín, Juan F., Liras, Paloma
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135043/
https://ncbi.nlm.nih.gov/pubmed/12003953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.11.3106-3113.2002
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