The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity.

Ítems similars

• A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds.
  per: Pérez-Llarena, F J, et al.
  Publicat: (1997)
• The pcd Gene Encoding Piperideine-6-Carboxylate Dehydrogenase Involved in Biosynthesis of α-Aminoadipic Acid Is Located in the Cephamycin Cluster of Streptomyces clavuligerus
  per: Pérez-Llarena, Francisco J., et al.
  Publicat: (1998)
• New type of hexameric ornithine carbamoyltransferase with arginase activity in the cephamycin producers Streptomyces clavuligerus and Nocardia lactamdurans.
  per: De la Fuente, J L, et al.
  Publicat: (1996)
• Molecular analysis of a beta-lactam resistance gene encoded within the cephamycin gene cluster of Streptomyces clavuligerus.
  per: Paradkar, A S, et al.
  Publicat: (1996)
• Cloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerus.
  per: García-Domínguez, M, et al.
  Publicat: (1991)