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Dilated cardiomyopathy (DCM) in the nmd mouse: Transgenic rescue and QTLs that improve cardiac function and survival.

Mutations in the immunoglobulin mu binding protein 2 (Ighmbp2) gene cause motor neuron disease and dilated cardiomyopathy (DCM) in the neuromuscular degeneration (nmd) mouse, and spinal muscular atrophy with respiratory distress (SMARD1) in humans. To investigate the role of IGHMBP2 in the pathogene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maddatu, Terry P., Garvey, Sean M., Schroeder, David G., Zhang, Wiedong, Kim, Soh-Yule, Nicholson, Anthony I., Davis, Crystal J., Cox, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350304/
https://ncbi.nlm.nih.gov/pubmed/16174646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddi349
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