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Dilated cardiomyopathy (DCM) in the nmd mouse: Transgenic rescue and QTLs that improve cardiac function and survival.

Mutations in the immunoglobulin mu binding protein 2 (Ighmbp2) gene cause motor neuron disease and dilated cardiomyopathy (DCM) in the neuromuscular degeneration (nmd) mouse, and spinal muscular atrophy with respiratory distress (SMARD1) in humans. To investigate the role of IGHMBP2 in the pathogene...

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Autors principals: Maddatu, Terry P., Garvey, Sean M., Schroeder, David G., Zhang, Wiedong, Kim, Soh-Yule, Nicholson, Anthony I., Davis, Crystal J., Cox, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1350304/
https://ncbi.nlm.nih.gov/pubmed/16174646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddi349
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