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Demonstration that fbiC Is Required by Mycobacterium bovis BCG for Coenzyme F(420) and FO Biosynthesis

Using the nitroimidazopyran-based antituberculosis drug PA-824 as a selective agent, transposon-generated Mycobacterium bovis strain BCG (M. bovis) mutants that could not make coenzyme F(420) were identified. Four independent mutants that could not make F(420) or the biosynthesis intermediate FO wer...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Choi, Kwang-Pil, Kendrick, Nathan, Daniels, Lacy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11948155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.9.2420-2428.2002
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