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Effects of Pyrazinamide on Fatty Acid Synthesis by Whole Mycobacterial Cells and Purified Fatty Acid Synthase I

The effects of low extracellular pH and intracellular accumulation of weak organic acids were compared with respect to fatty acid synthesis by whole cells of Mycobacterium tuberculosis and Mycobacterium smegmatis. The profile of fatty acids synthesized during exposure to benzoic, nicotinic, or pyraz...

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Detalhes bibliográficos
Main Authors: Boshoff, Helena I., Mizrahi, Valerie, Barry, Clifton E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134955/
https://ncbi.nlm.nih.gov/pubmed/11914348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.8.2167-2172.2002
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