Lack of Regulation of the Modification-Dependent Restriction Enzyme McrBC in Escherichia coli

Restriction alleviation (RA) by the type I restriction enzyme EcoKI is caused by treatments that damage DNA. RA is due to proteolysis of the EcoKI HsdR subunit by the ClpXP ATP-dependent protease. Here we show that the modification-dependent enzyme McrBC is not subject to RA, although it is moderate...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Murphy, Mark, Schmid Nuoffer, Stefanie, Bickle, Thomas A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Enzymes and Proteins
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11872734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.6.1794-1795.2002
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