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Lack of Regulation of the Modification-Dependent Restriction Enzyme McrBC in Escherichia coli

Restriction alleviation (RA) by the type I restriction enzyme EcoKI is caused by treatments that damage DNA. RA is due to proteolysis of the EcoKI HsdR subunit by the ClpXP ATP-dependent protease. Here we show that the modification-dependent enzyme McrBC is not subject to RA, although it is moderate...

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Detalhes bibliográficos
Main Authors: Murphy, Mark, Schmid Nuoffer, Stefanie, Bickle, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134900/
https://ncbi.nlm.nih.gov/pubmed/11872734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.6.1794-1795.2002
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