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Hybrid assemblies of ATP-sensitive K(+) channels determine their muscle-type-dependent biophysical and pharmacological properties

ATP-sensitive K(+) channels (K(ATP)) are an octameric complex of inwardly rectifying K(+) channels (Kir6.1 and Kir6.2) and sulfonylurea receptors (SUR1 and SUR2A/B), which are involved in several diseases. The tissue-selective expression of the subunits leads to different channels; however, the comp...

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書誌詳細
主要な著者: Tricarico, Domenico, Mele, Antonietta, Lundquist, Andrew L., Desai, Reshma R., George, Alfred L., Camerino, Diana Conte
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347972/
https://ncbi.nlm.nih.gov/pubmed/16418275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505974103
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