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Hybrid assemblies of ATP-sensitive K(+) channels determine their muscle-type-dependent biophysical and pharmacological properties
ATP-sensitive K(+) channels (K(ATP)) are an octameric complex of inwardly rectifying K(+) channels (Kir6.1 and Kir6.2) and sulfonylurea receptors (SUR1 and SUR2A/B), which are involved in several diseases. The tissue-selective expression of the subunits leads to different channels; however, the comp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1347972/ https://ncbi.nlm.nih.gov/pubmed/16418275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505974103 |
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