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Essential Role for Rac in Heregulin β1 Mitogenic Signaling: a Mechanism That Involves Epidermal Growth Factor Receptor and Is Independent of ErbB4

Heregulins are a family of ligands for the ErbB3/ErbB4 receptors that play important roles in breast cancer cell proliferation and tumorigenesis. Limited information is available on the contribution of Rho GTPases to heregulin-mediated signaling. In breast cancer cells, heregulin β1 (HRG) causes a s...

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Detalhes bibliográficos
Main Authors: Yang, Chengfeng, Liu, Ying, Lemmon, Mark A., Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347034/
https://ncbi.nlm.nih.gov/pubmed/16428439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.831-842.2006
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