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Accelerated Ovarian Failure Induced by 4-Vinyl Cyclohexene Diepoxide in Nrf2 Null Mice
Genetic and biochemical analyses have uncovered an essential role for nuclear factor erythroid 2-related factor 2 (Nrf2) in regulating phase II xenobiotic metabolism and antioxidant response. Here we show that Nrf2 protects against the ovarian toxicity of 4-vinylcyclohexene diepoxide (VCD) in mice....
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Autori principali: | , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology
2006
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1347017/ https://ncbi.nlm.nih.gov/pubmed/16428448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.940-954.2006 |
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