Conditional Loss of Nkx3.1 in Adult Mice Induces Prostatic Intraepithelial Neoplasia

The homeodomain-containing transcription factor NKX3.1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3.1 protein expression is common in human prostate carcinomas and prostatic intraepithelial neoplasia (PIN) lesion...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Abdulkadir, Sarki A., Magee, Jeffrey A., Peters, Thomas J., Kaleem, Zahid, Naughton, Cathy K., Humphrey, Peter A., Milbrandt, Jeffrey
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2002
Sujets:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1495-1503.2002
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