Conditional Loss of Nkx3.1 in Adult Mice Induces Prostatic Intraepithelial Neoplasia

The homeodomain-containing transcription factor NKX3.1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3.1 protein expression is common in human prostate carcinomas and prostatic intraepithelial neoplasia (PIN) lesion...

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Detalhes bibliográficos
Main Authors: Abdulkadir, Sarki A., Magee, Jeffrey A., Peters, Thomas J., Kaleem, Zahid, Naughton, Cathy K., Humphrey, Peter A., Milbrandt, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134699/
https://ncbi.nlm.nih.gov/pubmed/11839815
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