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Myxoma Virus M11L Blocks Apoptosis through Inhibition of Conformational Activation of Bax at the Mitochondria

Many viruses inhibit or retard apoptosis, a strategy that subverts one of the most ancient antiviral mechanisms. M11L, a myxoma virus-encoded antiapoptotic protein, has been previously shown to localize to mitochondria and block apoptosis of virus-infected cells (H. Everett, M. Barry, S. F. Lee, X....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Su, Jin, Wang, Gen, Barrett, John W., Irvine, Timothy S., Gao, Xiujuan, McFadden, Grant
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346952/
https://ncbi.nlm.nih.gov/pubmed/16414991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1140-1151.2006
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