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Paramyxovirus Receptor-Binding Molecules: Engagement of One Site on the Hemagglutinin-Neuraminidase Protein Modulates Activity at the Second Site

The hemagglutinin-neuraminidase (HN) protein of paramyxoviruses carries out three different activities: receptor binding, receptor cleaving (neuraminidase), and triggering of the fusion protein. These three discrete properties each affect the ability of HN to promote viral fusion and entry. For huma...

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Bibliographische Detailangaben
Hauptverfasser: Porotto, Matteo, Fornabaio, Micaela, Greengard, Olga, Murrell, Matthew T., Kellogg, Glen E., Moscona, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346948/
https://ncbi.nlm.nih.gov/pubmed/16414997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1204-1213.2006
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