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Inhibitor of Apoptosis Protein cIAP2 Is Essential for Lipopolysaccharide-Induced Macrophage Survival

The cellular inhibitor of apoptosis 2 (cIAP2/HIAP1) is a potent inhibitor of apoptotic death. In contrast to the other members of the IAP family, cIAP2 is transcriptionally inducible by nuclear factor-κB in response to multiple triggers. We demonstrate here that cIAP2(−/−) mice exhibit profound resi...

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Detalhes bibliográficos
Main Authors: Conte, Damiano, Holcik, Martin, Lefebvre, Charles A., LaCasse, Eric, Picketts, David J., Wright, Kathryn E., Korneluk, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346893/
https://ncbi.nlm.nih.gov/pubmed/16382159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.2.699-708.2006
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