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Phenotypic Complementation Establishes Requirements for Specific POU Domain and Generic Transactivation Function of Oct-3/4 in Embryonic Stem Cells

Transcription factors of the POU family govern cell fate through combinatorial interactions with coactivators and corepressors. The POU factor Oct-3/4 can define differentiation, dedifferentation, or self-renewal of pluripotent embryonic stem (ES) cells in a sensitive, dose-dependent manner (H. Niwa...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Niwa, Hitoshi, Masui, Shinji, Chambers, Ian, Smith, Austin G., Miyazaki, Jun-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134688/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1526-1536.2002
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