Phenotypic Complementation Establishes Requirements for Specific POU Domain and Generic Transactivation Function of Oct-3/4 in Embryonic Stem Cells

Transcription factors of the POU family govern cell fate through combinatorial interactions with coactivators and corepressors. The POU factor Oct-3/4 can define differentiation, dedifferentation, or self-renewal of pluripotent embryonic stem (ES) cells in a sensitive, dose-dependent manner (H. Niwa...

Full description

Saved in:
Bibliographic Details
Main Authors: Niwa, Hitoshi, Masui, Shinji, Chambers, Ian, Smith, Austin G., Miyazaki, Jun-ichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC134688/
https://ncbi.nlm.nih.gov/pubmed/11839818
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items