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Characterization of a Vaccinia Virus Mutant with a Deletion of the D10R Gene Encoding a Putative Negative Regulator of Gene Expression

The D9 and D10 proteins of vaccinia virus are 25% identical to each other, contain a mutT motif characteristic of nudix hydrolases, and are conserved in all sequenced poxviruses. Previous studies indicated that overexpression of D10 and, to a lesser extent, D9 decreased the levels of capped mRNAs an...

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Autores principales: Parrish, Susan, Moss, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346865/
https://ncbi.nlm.nih.gov/pubmed/16378957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.553-561.2006
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