UL54-Null Pseudorabies Virus Is Attenuated in Mice but Productively Infects Cells in Culture

The pseudorabies virus (PRV) UL54 homologs are important multifunctional proteins with roles in shutoff of host protein synthesis, transactivation of virus and cellular genes, and regulation of splicing and translation. Here we describe the first genetic characterization of UL54. We constructed UL54...

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Hlavní autoři: Schwartz, Jennifer A., Brittle, Elizabeth E., Reynolds, Ashley E., Enquist, Lynn W., Silverstein, Saul J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346835/
https://ncbi.nlm.nih.gov/pubmed/16378979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.769-784.2006
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