UL54-Null Pseudorabies Virus Is Attenuated in Mice but Productively Infects Cells in Culture

The pseudorabies virus (PRV) UL54 homologs are important multifunctional proteins with roles in shutoff of host protein synthesis, transactivation of virus and cellular genes, and regulation of splicing and translation. Here we describe the first genetic characterization of UL54. We constructed UL54...

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Detalhes bibliográficos
Main Authors: Schwartz, Jennifer A., Brittle, Elizabeth E., Reynolds, Ashley E., Enquist, Lynn W., Silverstein, Saul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346835/
https://ncbi.nlm.nih.gov/pubmed/16378979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.769-784.2006
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