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Integrin α2β1 Promotes Activation of Protein Phosphatase 2A and Dephosphorylation of Akt and Glycogen Synthase Kinase 3β

Serine/threonine kinase Akt is a downstream effector protein of phosphatidylinositol-3-kinase (PI-3K). Many integrins can function as positive modulators of the PI-3K/Akt pathway. Integrin α2β1 is a collagen receptor that has been shown to induce specific signals distinct from those activated by oth...

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Udgivet i:Mol Cell Biol
Principais autores: Ivaska, Johanna, Nissinen, Liisa, Immonen, Nina, Eriksson, John E., Kähäri, Veli-Matti, Heino, Jyrki
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1352-1359.2002
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