Integrin α2β1 Promotes Activation of Protein Phosphatase 2A and Dephosphorylation of Akt and Glycogen Synthase Kinase 3β

Serine/threonine kinase Akt is a downstream effector protein of phosphatidylinositol-3-kinase (PI-3K). Many integrins can function as positive modulators of the PI-3K/Akt pathway. Integrin α2β1 is a collagen receptor that has been shown to induce specific signals distinct from those activated by oth...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Ivaska, Johanna, Nissinen, Liisa, Immonen, Nina, Eriksson, John E., Kähäri, Veli-Matti, Heino, Jyrki
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1352-1359.2002
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