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Lack of Pharmacokinetic Interaction between Linezolid and Antacid in Healthy Volunteers

Several antibiotics show significant pharmacokinetic interactions when they are given orally concomitantly with antacids. The objective of this study was to evaluate the effects of antacid (containing magnesium) on the pharmacokinetics of linezolid. A single dose of 600 mg linezolid was given orally...

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Main Authors: Grunder, Gabriela, Zysset-Aschmann, Yvonne, Vollenweider, Florence, Maier, Thomas, Krähenbühl, Stephan, Drewe, Juergen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346802/
https://ncbi.nlm.nih.gov/pubmed/16377669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.68-72.2006
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