5-Nitroimidazole Drugs Effective against Metronidazole-Resistant Trichomonas vaginalis and Giardia duodenalis

Metronidazole (Mz)-resistant Giardia and Trichomonas were inhibited by 1 of 30 new 5-nitroimidazole drugs. Another five drugs were effective against some but not all of the Mz-resistant parasites. This study provides the incentive for the continued design of 5-nitroimidazole drugs to bypass cross-re...

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Bibliographic Details
Main Authors: Upcroft, Jacqueline A., Dunn, Linda A., Wright, Janelle M., Benakli, Kamel, Upcroft, Peter, Vanelle, Patrice
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346785/
https://ncbi.nlm.nih.gov/pubmed/16377707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.344-347.2006
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