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Induction and Inhibition of Ciprofloxacin Resistance-Conferring Mutations in Hypermutator Bacteria

The emergence of drug-resistant bacteria poses a serious threat to human health. Bacteria often acquire resistance from a mutation of chromosomal genes during therapy. We have recently shown that the evolution of resistance to ciprofloxacin in vivo and in vitro requires the induction of a mutation t...

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Detalhes bibliográficos
Main Authors: Cirz, Ryan T., Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346780/
https://ncbi.nlm.nih.gov/pubmed/16377689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.220-225.2006
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