Target Antigen, Age, and Duration of Antigen Exposure Independently Regulate Immunoglobulin G Subclass Switching in Malaria

The isotype/subclass of immunoglobulin determines antibody function, but rather little is known about factors that direct class switching in vivo. To evaluate factors that might influence the maturation of the antibody response during infection, we conducted a seroepidemiological study of the immuno...

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Hlavní autoři: Tongren, J. Eric, Drakeley, Christopher J., McDonald, Suzanna L. R., Reyburn, Hugh G., Manjurano, Alphaxard, Nkya, Watoky M. M., Lemnge, Martha M., Gowda, Channe D., Todd, Jim E., Corran, Patrick H., Riley, Eleanor M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346665/
https://ncbi.nlm.nih.gov/pubmed/16368979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.257-264.2006
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