Target Antigen, Age, and Duration of Antigen Exposure Independently Regulate Immunoglobulin G Subclass Switching in Malaria

The isotype/subclass of immunoglobulin determines antibody function, but rather little is known about factors that direct class switching in vivo. To evaluate factors that might influence the maturation of the antibody response during infection, we conducted a seroepidemiological study of the immuno...

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Autores principales: Tongren, J. Eric, Drakeley, Christopher J., McDonald, Suzanna L. R., Reyburn, Hugh G., Manjurano, Alphaxard, Nkya, Watoky M. M., Lemnge, Martha M., Gowda, Channe D., Todd, Jim E., Corran, Patrick H., Riley, Eleanor M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346665/
https://ncbi.nlm.nih.gov/pubmed/16368979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.257-264.2006
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