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Immunization with Persistent Attenuated Δlpg2 Leishmania major Parasites Requires Adjuvant To Provide Protective Immunity in C57BL/6 Mice

Leishmania major parasites lacking the GDP-mannose transporter, termed Δlpg2 parasites, fail to induce disease in mice but persist long-term. We previously found that Δlpg2 organisms protect BALB/c mice from virulent L. major challenge. In contrast, we report here that Δlpg2 parasites induce protect...

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Detalhes bibliográficos
Main Authors: Kébaïer, Chahnaz, Uzonna, Jude E., Beverley, Stephen M., Scott, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346616/
https://ncbi.nlm.nih.gov/pubmed/16369039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.777-780.2006
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