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Immunization with Persistent Attenuated Δlpg2 Leishmania major Parasites Requires Adjuvant To Provide Protective Immunity in C57BL/6 Mice
Leishmania major parasites lacking the GDP-mannose transporter, termed Δlpg2 parasites, fail to induce disease in mice but persist long-term. We previously found that Δlpg2 organisms protect BALB/c mice from virulent L. major challenge. In contrast, we report here that Δlpg2 parasites induce protect...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346616/ https://ncbi.nlm.nih.gov/pubmed/16369039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.777-780.2006 |
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