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Role of Hyaluronidase in Subcutaneous Spread and Growth of Group A Streptococcus

Group A streptococcus (GAS) depends on a hyaluronic acid (HA) capsule to evade phagocytosis and to interact with epithelial cells. Paradoxically, GAS also produces hyaluronidase (Hyl), an enzyme that cleaves HA. A common assumption is that Hyl digests structurally identical HA in human tissue to pro...

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Bibliographische Detailangaben
Hauptverfasser: Rivera Starr, Clarise, Engleberg, N. Cary
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346594/
https://ncbi.nlm.nih.gov/pubmed/16368955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.40-48.2006
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