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Functional Multimerization of Human Telomerase Requires an RNA Interaction Domain in the N Terminus of the Catalytic Subunit

Functional human telomerase complexes are minimally composed of the human telomerase RNA (hTR) and a catalytic subunit (human telomerase reverse transcriptase [hTERT]) containing reverse transcriptase (RT)-like motifs. The N terminus of TERT proteins is unique to the telomerase family and has been i...

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Autors principals: Moriarty, Tara J., Huard, Sylvain, Dupuis, Sophie, Autexier, Chantal
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134651/
https://ncbi.nlm.nih.gov/pubmed/11809815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.1253-1265.2002
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