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Functional Multimerization of Human Telomerase Requires an RNA Interaction Domain in the N Terminus of the Catalytic Subunit

Functional human telomerase complexes are minimally composed of the human telomerase RNA (hTR) and a catalytic subunit (human telomerase reverse transcriptase [hTERT]) containing reverse transcriptase (RT)-like motifs. The N terminus of TERT proteins is unique to the telomerase family and has been i...

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Udgivet i:Mol Cell Biol
Principais autores: Moriarty, Tara J., Huard, Sylvain, Dupuis, Sophie, Autexier, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11809815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.4.1253-1265.2002
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