Receptor Activator of NF-κB Ligand (RANKL) Activates TAK1 Mitogen-Activated Protein Kinase Kinase Kinase through a Signaling Complex Containing RANK, TAB2, and TRAF6

The receptor activator of NF-κB (RANK) and its ligand RANKL are key molecules for differentiation and activation of osteoclasts. RANKL stimulates transcription factors AP-1 through mitogen-activated protein kinase (MAPK) activation, and NF-κB through IκB kinase (IKK) activation. Tumor necrosis facto...

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Autori principali: Mizukami, Junko, Takaesu, Giichi, Akatsuka, Hiroyuki, Sakurai, Hiroaki, Ninomiya-Tsuji, Jun, Matsumoto, Kunihiro, Sakurai, Naoki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC134634/
https://ncbi.nlm.nih.gov/pubmed/11809792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.992-1000.2002
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