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Focal Adhesions Require Catalytic Activity of Src Family Kinases To Mediate Integrin-Matrix Adhesion

Members of the Src family of tyrosine kinases function to phosphorylate focal adhesion (FA) proteins. To explore the overlapping functions of Src kinases, we have targeted Csk, a negative regulator of the Src family, to FA structures. Expression of FA-targeted Csk (FA-Csk) effectively reduced the ac...

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Udgivet i:Mol Cell Biol
Principais autores: Li, Leiming, Okura, Masaya, Imamoto, Akira
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11809811/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.4.1203-1217.2002
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