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The Neurofibromatosis Type 2 Gene Product, merlin, Reverses the F-Actin Cytoskeletal Defects in Primary Human Schwannoma Cells

Schwannoma tumors, which occur sporadically and in patients with neurofibromatosis, account for 8% of intracranial tumors and can only be treated by surgical removal. Most schwannomas have biallelic mutations in the NF2 tumor suppressor gene. We previously showed that schwannoma-derived Schwann cell...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bashour, Anne-Marie, Meng, J.-J., Ip, Wallace, MacCollin, Mia, Ratner, Nancy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC134629/
https://ncbi.nlm.nih.gov/pubmed/11809806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.1150-1157.2002
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