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Molecular study of frequency of mosaicism in neurofibromatosis 2 patients with bilateral vestibular schwannomas

Neurofibromatosis 2 (NF2) is a severe autosomal dominant disorder that predisposes to multiple tumours of the nervous system. About half of all patients are founders with clinically unaffected parents. The purpose of the present study was to examine the extent to which mosaicism is present in NF2 fo...

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Detalhes bibliográficos
Main Authors: Kluwe, L, Mautner, V, Heinrich, B, Dezube, R, Jacoby, L, Friedrich, R, MacCollin, M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1735360/
https://ncbi.nlm.nih.gov/pubmed/12566519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.40.2.109
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