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Essential Roles in Development and Pigmentation for the Drosophila Copper Transporter DmATP7

Defects in the mammalian Menkes and Wilson copper transporting P-type ATPases cause severe copper homeostasis disease phenotypes in humans. Here, we find that DmATP7, the sole Drosophila orthologue of the Menkes and Wilson genes, is vital for uptake of copper in vivo. Analysis of a DmATP7 loss-of-fu...

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Autori principali: Norgate, Melanie, Lee, Esther, Southon, Adam, Farlow, Ashley, Batterham, Philip, Camakaris, James, Burke, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345683/
https://ncbi.nlm.nih.gov/pubmed/16251357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-06-0492
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