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Essential Roles in Development and Pigmentation for the Drosophila Copper Transporter DmATP7
Defects in the mammalian Menkes and Wilson copper transporting P-type ATPases cause severe copper homeostasis disease phenotypes in humans. Here, we find that DmATP7, the sole Drosophila orthologue of the Menkes and Wilson genes, is vital for uptake of copper in vivo. Analysis of a DmATP7 loss-of-fu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1345683/ https://ncbi.nlm.nih.gov/pubmed/16251357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-06-0492 |
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