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Different Plk1 Functions Show Distinct Dependencies on Polo-Box Domain-mediated Targeting

Polo-like kinase 1 (Plk1) has multiple important functions during M-phase progression. In addition to a catalytic domain, Plk1 possesses a phosphopeptide-binding motif, the polo-box domain (PBD), which is required for proper localization. Here, we have explored the importance of correct Plk1 subcell...

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Detalhes bibliográficos
Main Authors: Hanisch, Anja, Wehner, Anja, Nigg, Erich A., Silljé, Herman H.W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345681/
https://ncbi.nlm.nih.gov/pubmed/16267267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0801
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