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Rescue of Vasopressin V2 Receptor Mutants by Chemical Chaperones: Specificity and Mechanism
Because missense mutations in genetic diseases of membrane proteins often result in endoplasmic reticulum (ER) retention of functional proteins, drug-induced rescue of their cell surface expression and understanding the underlying mechanism are of clinical value. To study this, we tested chemical ch...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1345675/ https://ncbi.nlm.nih.gov/pubmed/16267275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-06-0579 |
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