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Proteolysis of Cortactin by Calpain Regulates Membrane Protrusion during Cell Migration

Calpain 2 regulates membrane protrusion during cell migration. However, relevant substrates that mediate the effects of calpain on protrusion have not been identified. One potential candidate substrate is the actin binding protein cortactin. Cortactin is a Src substrate that drives actin polymerizat...

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Hlavní autoři: Perrin, Benjamin J., Amann, Kurt J., Huttenlocher, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345662/
https://ncbi.nlm.nih.gov/pubmed/16280362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-06-0488
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