Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres

Telomere maintenance is essential for the continuous growth of tumor cells. In most human tumors telomeres are maintained by telomerase, a specialized reverse transcriptase. Tankyrase 1, a human telomeric poly(ADP-ribose) polymerase (PARP), positively regulates telomere length through its interactio...

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Autores principales: Cook, Brandoch D., Dynek, Jasmin N., Chang, William, Shostak, Grigoriy, Smith, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
DNA Dynamics and Chromosome Structure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC134233/
https://ncbi.nlm.nih.gov/pubmed/11739745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.332-342.2002
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